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Article

HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation.

Blood - 15 Jun 2005

Neil Stuart J D, McKnight Aine, Gustafsson Kenth, Weiss Robin A

Abstract excerpt

ABO histo-blood group antigens have been postulated to modify pathogen spread through the action of natural antibodies and complement. The antigens are generated by a polymorphic glycosyl-transferase encoded by 2 dominant active and a recessive inactive allele. In this study we investigated whether ABO sugars are incorporated into the envelope of HIV-1 virions. HIV vectors derived from cells expressing ABO...

Read the complete abstract on PubMed

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Share to ABO Blood-Group System
Share to Blood Group Antigens
Share to Complement Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glycosyltransferases

Share to HIV Envelope Protein gp120

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Source

Identifiers

PMID: 15728127
DOI: 10.1182/blood-2004-11-4267

Genes

ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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