Article
Transcriptional regulation through RfaH contributes to intestinal colonization by Escherichia coli.
FEMS microbiology letters - 1 Mar 2005
Nagy Gábor, Dobrindt Ulrich, Grozdanov Lubomir, Hacker Jörg, Emody Levente
Abstract excerpt
The Escherichia coli regulatory protein RfaH contributes to efficient colonization of the mouse gut. Extraintestinal pathogenic (ExPEC) as well as non-pathogenic probiotic E. coli strains rapidly outcompeted their isogenic rfaH mutants following oral mixed infections. LPS-core and O-antigen side-chain as well as capsular polysaccharide synthesis are among the E. coli virulence factors affected by RfaH. In respect...
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