Article
Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based comparative genomic hybridization.
Biochemical and biophysical research communications - 1 Apr 2005
Kawaguchi Kazunori, Honda Masao, Yamashita Taro, Shirota Yukihiro, Kaneko Shuichi
Abstract excerpt
We assayed chromosomal abnormalities in hepatoma cell lines using the microarray-based comparative genomic hybridization (array-CGH) method and investigated the relationship between genomic copy number alterations and expression profiles in these hepatoma cell lines. We modified a cDNA array-CGH assay to compare genomic DNAs from seven hepatoma cell lines, as well as DNA from two non-hepatoma cell lines and from...
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