Article
Video assisted prophylactic thyroidectomy and central compartment nodes clearance in two RET gene mutation adult carriers.
Journal of endocrinological investigation - 1 Jun 2004
Miccoli P, Elisei R, Berti P, Materazzi G, Agate L, Castagna M G, Cosci B, Faviana P, Ugolini C, Pinchera A
Abstract excerpt
Activating point mutations of RET gene have been demonstrated to be causative of the familial form of medullary thyroid cancer (MTC), both isolated (FMTC) and associated to other endocrine neoplasia [multiple endocrine neoplasia (MEN) 2A and 2B]. In RET gene mutation carriers, who are prone to developing MTC, prophylactic thyroidectomy is recommended to obtain their definitive cure. The simultaneous excision of...
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