Article
Multiple endocrine neoplasias type 2A and thyroid medullary carcinoma: an interdisciplinary challenge.
Pediatric surgery international - 1 Apr 2003
Haecker Frank-Martin, Oertli Daniel, Gissler Stefanie, Zumsteg Urs, Avoledo Pierino, von Schweinitz Dietrich
Abstract excerpt
The diagnosis and treatment of multiple endocrine neoplasias type 2A (MEN 2A) requires interdisciplinary management. The association of RET proto-oncogene mutations and medullary thyroid carcinoma (MTC) in children is well-known, but the optimal timing for elective surgery is controversial. Besides the risk of MTC, associated anomalies like hyperparathyroidism have to be considered. We report the results of...
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