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Article

Pseudogene accumulation might promote the adaptive microevolution of Yersinia pestis.

Journal of medical microbiology - 1 Mar 2005

Tong Zongzhong, Zhou Dongsheng, Song Yajun, Zhang Ling, Pei Decui, Han Yanping, Pang Xin, Li Min, Cui Baizhong, Wang Jin, Guo Zhaobiao, Qi Zhizhen, Jin Lixia, Zhai Junhui, Du Zongmin, Wang Jun, Wang Xiaoyi, Yu Jun, Wang Jian, Huang Peitang, Yang Huanming, Yang Ruifu

Abstract excerpt

Plague is a natural focus-based disease, and for better understanding of this disease it is crucial to determine the molecular mechanisms of its pathogen, Yersinia pestis, for adapting to different foci. Gene inactivation, loss and acquisition are the main mechanisms that contribute to a pathogen's fitness. Determination of the whole-genome sequences of three Y. pestis strains, CO92, KIM and 91001, provided a...

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Identifiers

PMID: 15713609
DOI: 10.1099/jmm.0.45752-0

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