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Article

MDR and PRP: a comparison of methods for high-order genotype-phenotype associations.

Human heredity - 1 Jan 2004

Bastone L, Reilly M, Rader D J, Foulkes A S

Abstract excerpt

Complex diseases such as cardiovascular disease are likely due to the effects of high-order interactions among multiple genes and demographic factors. Therefore, in order to understand their underlying biological mechanisms, we need to consider simultaneously the effects of genotypes across multiple loci. Statistical methods such as multifactor dimensionality reduction (MDR), the combinatorial partitioning method...

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PMID: 15711088
DOI: 10.1159/000083029

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CPM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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