Article
A family-based association study does not support DYX1C1 on 15q21.3 as a candidate gene in developmental dyslexia.
European journal of human genetics : EJHG - 1 Apr 2005
Marino Cecilia, Giorda Roberto, Luisa Lorusso Maria, Vanzin Laura, Salandi Nello, Nobile Maria, Citterio Alessandra, Beri Silvana, Crespi Valentina, Battaglia Marco, Molteni Massimo
Abstract excerpt
We applied a family-based association approach to investigate the role of the DYX1C1 gene on chromosome 15q as a candidate gene for developmental dyslexia (DD) to 158 families containing at least one dyslexic child. We directly sequenced exons 2 and 10 of the DYX1C1 gene and found eight single nucleotide polymorphism (SNPs), three of which (-3G>A, 1249 G>T, 1259 C>G) were suitable for the genetic analyses. We...
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