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Article

A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 2003

Taipale Mikko, Kaminen Nina, Nopola-Hemmi Jaana, Haltia Tuomas, Myllyluoma Birgitta, Lyytinen Heikki, Muller Kurt, Kaaranen Minna, Lindsberg Perttu J, Hannula-Jouppi Katariina, Kere Juha

Abstract excerpt

Approximately 3-10% of people have specific difficulties in reading, despite adequate intelligence, education, and social environment. We report here the characterization of a gene, DYX1C1 near the DYX1 locus in chromosome 15q21, that is disrupted by a translocation t(2;15)(q11;q21) segregating coincidentally with dyslexia. Two sequence changes in DYX1C1, one involving the translation initiation sequence and an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12954984
DOI: 10.1073/pnas.1833911100
PMCID: PMC208796

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TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain.PMID 12954984Read ↗

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