Article
Changes in fecal elastase-1 following initiation of CFTR modulator therapy in pediatric patients with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Nov 2023
Stephenson Kimberly G, Lingle Abby J, Baumberger Kelly A, Dellon Elisabeth P, Esther Charles R, Meier Ellen M, Oermann Christopher M, Shenoy Vivek K, Smith Natalie R, Wimmer Nicole S, Duehlmeyer Stephanie R, Kam Charissa W, McKinzie Cameron J, Poisson Margaret O, Elson E Claire
Abstract excerpt
BACKGROUND: Improvement in exocrine pancreatic function in persons with CF (pwCF) on cystic fibrosis transmembrane conductance regulator (CFTR) modulators has been documented in clinical trials using fecal pancreatic elastase-1 (FE-1). Our group endeavored to evaluate real-world data on FE-1 in children on CFTR modulator therapy at three pediatric cystic fibrosis (CF) centers. METHODS: Pediatric pwCF were offered...
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