Confirmation of the association of the C4B null allelle in autism.

doi:10.1016/j.humimm.2004.11.002

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Article

Confirmation of the association of the C4B null allelle in autism.

Human immunology - 1 Feb 2005

Odell Dennis, Maciulis Alma, Cutler Adele, Warren Louise, McMahon William M, Coon Hilary, Stubbs Gene, Henley Kathy, Torres Anthony

Abstract excerpt

The objective of this study was to examine and attempt to confirm our previous findings of an increased frequency of the C4B null allele (C4BQ0) in subjects with autism. Newly identified subjects from Utah and Oregon were studied. Families evaluated included 85 who had a child with autism and 69 control families. Of the subjects with autism studied, 42.4% carried at least one C4BQ0, compared with 14.5% of the...

Topics

Autistic Disorder
Complement C4b
Gene Frequency
Genotype
Histocompatibility Antigens
Humans
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 15694999
DOI: 10.1016/j.humimm.2004.11.002

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