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Article

Nude mutation influences limb skeletal muscle development.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jan 2005

Morrison Jamie, Partridge Terence, Bou-Gharios George

Abstract excerpt

The nude mouse lacks functional T cells and other skin defects due to the absence of Foxn1 transcription factor. The mdx mouse bred onto a nude background (Foxn1-/-), to generate mdx nu/nu, serves as a valuable model for the use in muscle cell transplantation or gene therapy studies, to avoid a detrimental immune response. However, it has been shown previously that the mdx nu/nu mice have a skeletal muscle...

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PMID: 15694130
DOI: 10.1016/j.matbio.2004.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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