Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin 10 and interleukin 3.

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Article

Transcriptional regulation of the mucosal mast cell-specific protease gene, MMCP-2, by interleukin 10 and interleukin 3.

The Journal of biological chemistry - 25 Apr 1992

Ghildyal N, McNeil H P, Gurish M F, Austen K F, Stevens R L

Abstract excerpt

Although transcription of mast cell (MC) secretory granule neutral protease genes has been shown to distinguish MC subclasses in mucosal and serosal environments, the specific cytokines that regulate the expression of these genes have not been determined. To examine cytokine-mediated gene regulat...

Topics

Animals
Base Sequence
Blotting, Northern
Bone Marrow Cells
Endopeptidases
Gene Expression Regulation
Interleukin-10
Interleukin-3
Interleukin-4
Mast Cells
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mucous Membrane

Phenotype

RNA, Messenger

Recombinant Proteins

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 1569097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1569097-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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