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Article

Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation

1 Feb 2005

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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15688043
DOI: 10.1038/nri1553

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Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporationPMID 15688043Read ↗

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FFPE DNA shows two major error profiles derived from deamination of cytosine and methylcytosine that can be mitigated using distinct repair strategiesSemantic proximity Read ↗

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Somatic hypermutation: processivity of the cytosine deaminase AID and error-free repair of the resulting uracils.Semantic proximity Read ↗

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