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Article

Identification of a molecular signature of sarcopenia

2 Feb 2005

Abstract excerpt

Investigating the molecular mechanisms underlying sarcopenia in humans with the use of microarrays has been complicated by low sample size and the variability inherent in human gene expression profiles. We have conducted a study using Affymetrix GeneChips to identify a molecular signature of aged skeletal muscle. The molecular signature was defined as the set of expressed genes that best distinguished the vastus...

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PMID: 15687482
DOI: 10.1152/physiolgenomics.00249.2004

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