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Predictive models of sarcopenia based on inflammation and pyroptosis-related genes

24 Dec 2024

Abstract excerpt

Background: Sarcopenia is a prevalent condition associated with aging. Inflammation and pyroptosis significantly contribute to sarcopenia. Methods: Two sarcopenia-related datasets (GSE111016 and GSE167186) were obtained from the Gene Expression Omnibus (GEO), followed by batch effect removal post-merger. The "limma" R package was utilized to identify differentially expressed genes (DEGs). Subsequently, LASSO...

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PMID: 39777262
DOI: 10.3389/fgene.2024.1491577

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