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Article

Mutational analysis of the disulfide catalysts DsbA and DsbB.

Journal of bacteriology - 1 Feb 2005

Tan Jacqueline, Lu Ying, Bardwell James C A

Abstract excerpt

In prokaryotes, disulfides are generated by the DsbA-DsbB system. DsbB functions to generate disulfides by quinone reduction. These disulfides are passed to the DsbA protein and then to folding proteins. To investigate the DsbA-DsbB catalytic system, we performed an in vivo selection for chromosomal dsbA and dsbB mutants. We rediscovered many residues previously shown to be important for the activity of these...

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Source

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Identifiers

PMID: 15687215
DOI: 10.1128/JB.187.4.1504-1510.2005
PMCID: PMC545614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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