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Article

Involvement of the pentose phosphate pathway and redox regulation in fertilization in the mouse

1 Jan 2005

Abstract excerpt

Glucose metabolism is necessary for successful fertilization in the mouse. Both spermatozoa and oocytes metabolize glucose through the pentose phosphate pathway (PPP), and NADPH appears required for gamete fusion. The aims of this study were to further characterize the utilization of glucose by the fertilizing spermatozoon and the fertilized oocyte, to demonstrate the importance of the PPP in different steps of...

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PMID: 15685628
DOI: 10.1002/mrd.20222

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