Up-Regulation of Glucose Metabolism During Male Pronucleus Formation Determines the Early Onset of the S Phase in Bovine Zygotes1

Abstract excerpt

After in vitro fertilization with spermatozoa from bulls with high in vitro fertility, a beneficial paternal effect is manifested during the G1 phase of the first cell cycle. This benefit determines an earlier onset of the first S phase, and then a successful morula-blastocyst transition 7 days later. We hypothesized that the origin of the paternal effect could be a shift of the metabolism of the fertilized...

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