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Article

A statistical method to detect chromosomal regions with DNA copy number alterations using SNP-array-based CGH data.

Computational biology and chemistry - 1 Feb 2005

Lai Yinglei, Zhao Hongyu

Abstract excerpt

Single nucleotide polymorphism (SNP) arrays were used to detect chromosomal regions with DNA copy number alterations. Current statistical methods for microarray-based comparative genomic hybridization (array-CGH) analysis generally assume certain relationships among adjacent markers on the same chromosome, and these assumptions may be questionable. For an SNP-array-based CGH study, multiple normal reference SNP...

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Identifiers

PMID: 15680585
DOI: 10.1016/j.compbiolchem.2004.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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