Article
Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data.
Bioinformatics (Oxford, England) - 1 May 2005
Lottaz Claudio, Spang Rainer
Abstract excerpt
MOTIVATION: Today, the characterization of clinical phenotypes by gene-expression patterns is widely used in clinical research. If the investigated phenotype is complex from the molecular point of view, new challenges arise and these have not been addressed systematically. For instance, the same clinical phenotype can be caused by various molecular disorders, such that one observes different characteristic...
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