Article
CXCR4 mutations in WHIM syndrome: a misguided immune system?
Immunological reviews - 1 Feb 2005
Diaz George A
Abstract excerpt
Chemokines and their receptors are key molecules in the development and function of immune cell populations and the organization of lymphoid organs. Despite their central role in immunologic function, genetic studies exploring the intersection of chemokines or their receptors and human health have revealed few associations of unambiguous significance. The best-characterized examples have revealed striking...
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