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Article

Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study.

American journal of human genetics - 1 Mar 2005

Reiner Alexander P, Ziv Elad, Lind Denise L, Nievergelt Caroline M, Schork Nicholas J, Cummings Steven R, Phong Angie, Burchard Esteban González, Harris Tamara B, Psaty Bruce M, Kwok Pui-Yan

Abstract excerpt

U.S. populations are genetically admixed, but surprisingly little empirical data exists documenting the impact of such heterogeneity on type I and type II error in genetic-association studies of unrelated individuals. By applying several complementary analytical techniques, we characterize genetic background heterogeneity among 810 self-identified African American subjects sampled as part of a multisite cohort...

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Identifiers

PMID: 15660291
DOI: 10.1086/428654
PMCID: PMC1196398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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