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Article

Statistical tests of the coalescent model based on the haplotype frequency distribution and the number of segregating sites.

Genetics - 1 Mar 2005

Innan Hideki, Zhang Kangyu, Marjoram Paul, Tavaré Simon, Rosenberg Noah A

Abstract excerpt

Several tests of neutral evolution employ the observed number of segregating sites and properties of the haplotype frequency distribution as summary statistics and use simulations to obtain rejection probabilities. Here we develop a "haplotype configuration test" of neutrality (HCT) based on the full haplotype frequency distribution. To enable exact computation of rejection probabilities for small samples, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15654103
DOI: 10.1534/genetics.104.032219
PMCID: PMC1449527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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