Article
Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study.
Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2005
Petzold A, Eikelenboom M J, Keir G, Grant D, Lazeron R H C, Polman C H, Uitdehaag B M J, Thompson E J, Giovannoni G
Abstract excerpt
BACKGROUND: Neurofilament phosphoforms (Nf) are principal components of the axoskeleton released during axonal injury. Cerebrospinal fluid (CSF) levels of Nf phosphoforms might be useful surrogate markers for disability in multiple sclerosis (MS), aid in distinguishing clinical subtypes, and provide valuable prognostic information. METHOD: Thirty four patients with MS were included in a three year follow up study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.