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Article

[Association between mutation of phospholamban gene and dilated cardiomyopathy].

Yi chuan = Hereditas - 1 Sept 2004

Zhao Chun-Xia, Cui Ying-Hua, Zhu Zhi-Hui, Wang Dao-Wen

Abstract excerpt

Phospholamban (PLB) is a prominent regulator of myocardial contractility and a reversible inhibitor of the cardiac sarcoplasmic reticulum Ca2+ ATPase activity. In normal cardiac muscles, phospholamban can be phosphorylated at distinct sites by various protein kinases and release its inhibition to sarcoplasmic reticulum Ca2+ ATPase. The studies of pedigrees have shown dilated cardiomyopathy (DCM) is related with...

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PMID: 15640069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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