Article
Cancer cell line identification by short tandem repeat profiling: power and limitations.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2005
Parson Walther, Kirchebner Romana, Mühlmann Roswitha, Renner Kathrin, Kofler Anita, Schmidt Stefan, Kofler Reinhard
Abstract excerpt
Cancer cell lines are used worldwide in biological research, and data interpretation depends on unambiguous attribution of the respective cell line to its original source. Short-tandem-repeat (STR) profiling (DNA fingerprinting) is the method of choice for this purpose; however, the genetic stability of cell lines under various experimental conditions is not well defined. We tested the effect of long-term...
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