Article
[Hereditary predispositions to gynaecological cancers].
Gynecologie, obstetrique & fertilite - 1 Nov 2005
Coupier I, Pujol P
Abstract excerpt
The breast, ovary and endometrial cancers are hereditary in 5 to 10% of the cases. These genetic predisposition syndromes can be classified into two major classes: ovarian cancer and breast cancer predisposition family cases (genes BRCA1 and BRCA2) and family cases of colon cancer, endometrial cancer and ovarian cancer (Lynch syndrome or HNPCC) (genes hMLH1, hMSH2, hMLH6). The estimate of the family and...
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