Article
Gene Expression of Early Hypertrophic Scar Tissue Screened by Means of cDNA Microarrays
1 Dec 2004
Abstract excerpt
BACKGROUND: Hypertrophic scar is an excessive healing response that often follows thermal injury. The most outstanding morphologic change is the overdeposition of collagen, which is caused by imbalance between synthesis and metabolism of collagen. Previous studies also found that transforming growth factor-beta was the key factor controlling scar formation. However, neither anti-transforming growth factor-beta...
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