Article
Mast-cell phenotype in indolent forms of mastocytosis. Ultrastructural features, fluorescence detection of avidin binding, and immunofluorescent determination of chymase, tryptase, and carboxypeptidase.
The American journal of pathology - 1 Apr 1992
Weidner N, Horan R F, Austen K F
Abstract excerpt
The factor(s) that causes excessive mast cell (MC) proliferation in indolent forms of mastocytosis is not known, nor is it known whether that proliferation is a regulated clonal expansion or merely a non-neoplastic hyperplasia. Human MCs display phenotypes that depend on the microenvironment. Thu...
Topics
- Avidin
- Bone Marrow
- Carboxypeptidases
- Chymases
- Dermatitis
- Fluorescent Antibody Technique
- Humans
- Mast Cells
- Mastocytosis
- Microscopy, Electron
- Peptide Hydrolases
- Phenotype
- Serine Endopeptidases
- Skin