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Article

Dermal mast cells in scleroderma: their skin density, tryptase/chymase phenotypes and degranulation.

The British journal of dermatology - 1 Mar 1998

Akimoto S, Ishikawa O, Igarashi Y, Kurosawa M, Miyachi Y

Abstract excerpt

To determine the distribution, tryptase/chymase phenotypes and degranulation of mast cells (MCs) in the dermis of patients with scleroderma, we examined MC density in the skin of 22 patients with systemic sclerosis (SSc) and 11 with localized scleroderma (LSc). We used antitryptase and antichymase antibodies after Carnoy's fixation. Detailed reports of two representative patients with SSc and LSc are included. In...

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Identifiers

PMID: 9580789
DOI: 10.1046/j.1365-2133.1998.02114.x

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