Article
Dermal mast cells in scleroderma: their skin density, tryptase/chymase phenotypes and degranulation.
The British journal of dermatology - 1 Mar 1998
Akimoto S, Ishikawa O, Igarashi Y, Kurosawa M, Miyachi Y
Abstract excerpt
To determine the distribution, tryptase/chymase phenotypes and degranulation of mast cells (MCs) in the dermis of patients with scleroderma, we examined MC density in the skin of 22 patients with systemic sclerosis (SSc) and 11 with localized scleroderma (LSc). We used antitryptase and antichymas...
Topics
- Adult
- Aged
- Cell Count
- Cell Degranulation
- Chymases
- Edema
- Female
- Humans
- Immunoenzyme Techniques
- Male
- Mast Cells
- Middle Aged
- Phenotype
- Scleroderma, Localized
- Scleroderma, Systemic
- Serine Endopeptidases
- Skin Diseases
- Tryptases