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Article

Pathways of tau fibrillization.

Biochimica et biophysica acta - 3 Jan 2005

Kuret Jeff, Chirita Carmen N, Congdon Erin E, Kannanayakal Theresa, Li Guibin, Necula Mihaela, Yin Haishan, Zhong Qi

Abstract excerpt

New methods for analyzing tau fibrillization have yielded insights into the biochemical transitions involved in the process. Here we review the parallels between the sequential progression of tau fibrillization observed macroscopically in Alzheimer's disease (AD) lesions and the pathway of tau aggregation observed in vitro with purified tau preparations. In addition, pharmacological agents for further dissection...

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Source

Identifiers

PMID: 15615636
DOI: 10.1016/j.bbadis.2004.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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