Article
Male pseudohermaphroditism in XY children with female phenotype.
Pediatric pathology - 1 Jan 2000
Bale P M, Howard N J, Wright J E
Abstract excerpt
Twenty-two children with female external genitalia, testes, and 46,XY karyotype, most presenting with inguinal lumps or hernias, underwent bilateral gonadal excision (21 patients) or biopsy. On clinical and biochemical grounds, 13 were classed as androgen resistance (AR), 6 as testosterone biosynthetic defect, 2 as XY gonadal dysgenesis, and 1 as 5 alpha-reductase deficiency. The main pathological difference...
Topics
- Adolescent
- Biopsy
- Child
- Child, Preschool
- Disorders of Sex Development
- Female
- Humans
- Infant
- Infant, Newborn
- Leydig Cells
- Male
- Phenotype
- Retrospective Studies