Article
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.
Pharmacogenetics - 1 Dec 2004
Paynter Randi A, Hankinson Susan E, Colditz Graham A, Hunter David J, De Vivo Immaculata
Abstract excerpt
Endogenous oestrogens play a crucial role in endometrial cancer pathogenesis, with most endometrial cancer risk factors causing an increase in oestrogens. Adipose tissue, where androgens are converted to oestrogens by the enzyme aromatase, is an important source of endogenous oestrogen production...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
