Emergent trade-offs and selection for outbreak frequency in spatial epidemics

Abstract excerpt

Nonspatial theory on pathogen evolution generally predicts selection for maximal number of secondary infections, constrained only by supposed physiological trade-offs between pathogen infectiousness and virulence. Spread of diseases in human populations can, however, exhibit large scale patterns, underlining the need for spatially explicit approaches to pathogen evolution. Here, we show, in a spatial model where...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Evolution and Genetic Dynamics
• Share to Evolutionary Game Theory and Cooperation
• Share to Mathematical and Theoretical Epidemiology and Ecology Models