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Article

Mutation analysis of TBX22 reveals new mutation in Tunisian CPX family.

Clinical dysmorphology - 1 Jan 2005

Chaabouni Myriam, Smaoui Nizar, Benneji Neila, M'rad Ridha, Jemaa Lamia Ben, Hachicha Slah, Chaabouni Habiba

Abstract excerpt

Cleft palate with ankyloglossia (CPX; OMIM 303400) is inherited as a Mendelian semidominant X-Linked disorder. Linkage studies resulted in mapping CPX to Xq13-q 21-31 region. TBX22 was identified as causing CPX. We report a new mutation in a Tunisian family and the first Arab family with X-Linked cleft palate and ankyloglossia. The family includes 6 affected members, 4 males and 2 females. Linkage study was...

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Identifiers

PMID: 15602089

Genes

TBX22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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