Article
Avian glutamine phosphoribosylpyrophosphate amidotransferase propeptide processing and activity are dependent upon essential cysteine residues.
The Journal of biological chemistry - 15 Apr 1992
Zhou G, Broyles S S, Dixon J E, Zalkin H
Abstract excerpt
Avian glutamine phosphoribosylpyrophosphate amidotransferase contains an NH2-terminal propetide-like sequence. NH2-terminal sequence analysis of immunoaffinity purified enzyme from chicken liver indicates that the propeptide is processed and the mature enzyme starts with Cys. Propeptide processin...
Topics
- Amidophosphoribosyltransferase
- Amino Acid Sequence
- Animals
- Blotting, Western
- Chickens
- Cysteine
- DNA
- Escherichia coli
- Gene Expression
- Genes, Bacterial
- HeLa Cells
- Humans
- Liver
- Molecular Sequence Data
- Mutation
- Plasmids
- Precipitin Tests
- Protein Precursors