Article
Molecular origins of rapid and continuous morphological evolution.
Proceedings of the National Academy of Sciences of the United States of America - 28 Dec 2004
Fondon John W, Garner Harold R
Abstract excerpt
Mutations in cis-regulatory sequences have been implicated as being the predominant source of variation in morphological evolution. We offer a hypothesis that gene-associated tandem repeat expansions and contractions are a major source of phenotypic variation in evolution. Here, we describe a comparative genomic study of repetitive elements in developmental genes of 92 breeds of dogs. We find evidence for...
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