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Article

Altered expression of cell cycle genes distinguishes aggressive neuroblastoma.

Oncogene - 24 Feb 2005

Krasnoselsky Alexei L, Whiteford Craig C, Wei Jun S, Bilke Sven, Westermann Frank, Chen Qing-Rong, Khan Javed

Abstract excerpt

In this study, gene expression profiling was performed on 103 neuroblastoma (NB) tumors, stages 1-4 with and without MYCN amplification, using cDNA microarrays containing 42,578 elements. Using principal component analysis (PCA) to analyse the relationships among these samples, we confirm that the global patterns of gene expression reflect the phenotype of the tumors. To explore the biological processes that may...

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Share to Cell Cycle
Share to Chromosome Segregation
Share to Chromosomes, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, myc

Share to Neoplasm Staging

Share to Neuroblastoma

Share to Oligonucleotide Array Sequence Analysis

Source

Identifiers

PMID: 15592497
DOI: 10.1038/sj.onc.1208341

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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