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Article

Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2005

Priore Oliva Claudio, Pisciotta Livia, Li Volti Giovanni, Sambataro Maria Paola, Cantafora Alfredo, Bellocchio Antonella, Catapano Alberico, Tarugi Patrizia, Bertolini Stefano, Calandra Sebastiano

Abstract excerpt

OBJECTIVE: Mutations in LPL or APOC2 genes are recognized causes of inherited forms of severe hypertriglyceridemia. However, some hypertrigliceridemic patients do not have mutations in either of these genes. Because inactivation or hyperexpression of APOA5 gene, encoding apolipoprotein A-V (apoA-V), causes a marked increase or decrease of plasma triglycerides in mice, and because some common polymorphisms of this...

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Source

Identifiers

PMID: 15591215
DOI: 10.1161/01.ATV.0000153087.36428.dd

Genes

APOA5
LPL
APOC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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