Article
Genetic variability in ESAG6 genes among Trypanosoma evansi isolates and in comparison to other Trypanozoon members.
Acta tropica - 1 Jan 2005
Witola William H, Sarataphan Nopporn, Inoue Noboru, Ohashi Kazuhiko, Onuma Misao
Abstract excerpt
Bloodstream trypanosomes take up iron needed for their propagation through the transferrin receptor that, in Trypanosoma brucei, is encoded by expression-site-associated genes (ESAGs), ESAG6 and 7 genes located in variant surface glycoprotein expression sites. ESAG6 and 7 genes in different expression sites have been shown to encode transferrin receptors with varying affinities for polymorphic transferrins. T....
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