Article
The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.
European journal of immunology - 1 Jan 2005
Gómez-Lozano Natalia, Estefanía Ernesto, Williams Fionnuala, Halfpenny Iris, Middleton Derek, Solís Rosario, Vilches Carlos
Abstract excerpt
Killer-cell Ig-like receptors (KIR) are structurally and functionally diverse, and enable human NK cells to survey the expression of individual HLA class I molecules, often altered in infections and tumors. Multiple events of non-reciprocal recombination have contributed to the rapid diversificat...
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