Article
Repression of fibroblast growth factor receptor 1 gene expression by E2F4 in skeletal muscle cells.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2005
Parakati Rajini, Dimario Joseph X
Abstract excerpt
Fibroblast growth factor receptor 1 (FGFR1) gene expression is positively and negatively regulated during muscle differentiation. We recently reported that FGFR1 gene expression was up-regulated by Sp transcription factors in proliferating myoblasts. However, the mechanism of down-regulation of this gene during differentiation is unknown. We have identified the transcription factor E2F4 as a negative regulator of...
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