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Induction of adipocyte-like phenotype in human mesenchymal stem cells by hypoxia.

Stem cells (Dayton, Ohio) - 1 Jan 2004

Fink Trine, Abildtrup Lisbeth, Fogd Kirsten, Abdallah Basem M, Kassem Moustapha, Ebbesen Peter, Zachar Vladimir

Abstract excerpt

Human mesenchymal stem cells (hMSCs) have the capacity to differentiate along several pathways to form bone, cartilage, tendon, muscle, and adipose tissues. The adult hMSCs reside in vivo in the bone marrow in niches where oxygen concentration is far below the ambient air, which is the most commonly encountered laboratory condition. The study reported here was designed to determine whether oxygen has a role in...

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PMID: 15579652
DOI: 10.1634/stemcells.2004-0038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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