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Article

Implications of exercise training in mtDNA defects--use it or lose it?

Biochimica et biophysica acta - 6 Dec 2004

Taivassalo Tanja, Haller Ronald G

Abstract excerpt

Whether regular exercise is beneficial or should be avoided is a question currently unsettled in patients with heteroplasmic mitochondrial DNA (mtDNA) disorders of skeletal muscle. Deleterious effects of habitual physical inactivity superimposed upon impaired mitochondrial oxidative phosphorylation may contribute to varying degrees of exercise intolerance in these patients. Endurance exercise training is widely...

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PMID: 15576055
DOI: 10.1016/j.bbabio.2004.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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