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Article

Matrix composition of cartilaginous anlagen in achondrogenesis type II (Langer-Saldino).

Frontiers in bioscience : a journal and virtual library - 1 Jan 2005

Dertinger Susanne, Söeder Stephan, Bösch Hubert, Aigner Thomas

Abstract excerpt

Skeletal dysplasias represent in vivo models of genetic defects. Achondrogenesis type II (Langer-Saldino), caused by a genetic defect in the major cartilage matrix protein, collagen type II, is a rare and severe skeletal dysplasia. It comprises a severe derangement of the fetal growth plate cartilage with subsequent ossification defects. In this study, we analyzed the matrix composition and cell differentiation...

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Identifiers

PMID: 15574381
DOI: 10.2741/1540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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