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Article

Molecular and Cellular Mechanisms of KSHV Oncogenesis of Kaposi's Sarcoma Associated with HIV/AIDS

10 Jul 2014

Abstract excerpt

AIDS-Associated Kaposi's Sarcoma: An Oncogenic Consequence of Infection with KSHV and HIVTwenty years after its discovery [1], Kaposi's sarcoma herpesvirus (KSHV) or human herpesvirus-8 (HHV-8) continues to be an enigmatic oncovirus, while AIDS-associated Kaposi's sarcoma (AIDS-KS) remains a clinical challenge in endemic regions in Africa and for some patients receiving anti-retroviral therapy (ART) [2-4].KSHV, a...

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PMID: 25010730
DOI: 10.1371/journal.ppat.1004154

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