Article
p53 and DPC4 alterations in the bile of patients with pancreatic carcinoma.
Journal of surgical oncology - 15 Dec 2004
Pantalone Desiree, Pelo Elisbetta, Minuti Barbara, Giotti Irene, Mazza Ernesto, Falchini Massimo, Neri Bruno, Nesi Gabriella, Roberta Girardi Lucia, Pulli Raffaele, Credi Giovanni, Torricelli Francesca
Abstract excerpt
INTRODUCTION: Pancreatic cancer is still predominantly diagnosed in advanced stages, and 85%-90% of patients are not eligible for surgery at diagnosis. This is mainly due to the great difficulty in detecting the tumour at an early stage and presently no satisfactory results have been obtained to overcome this problem. Studies on molecular genetic profile of pancreatic cancer may represent an important approach....
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