Article
Lig4 and rad54 are required for repair of DNA double-strand breaks induced by P-element excision in Drosophila.
Genetics - 1 Feb 2005
Romeijn Ron J, Gorski Marcin M, van Schie Martijn A, Noordermeer Jasprina N, Mullenders Leon H, Ferro Wouter, Pastink Albert
Abstract excerpt
Site-specific double-strand breaks (DSBs) were generated in the white gene located on the X chromosome of Drosophila by excision of the w(hd) P-element. To investigate the role of nonhomologous end joining (NHEJ) and homologous recombination (HR) in the repair of these breaks, the w(hd) P-element...
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