Article

Proteomic profile of nuclei containing p62-positive inclusions in neuronal intranuclear inclusion disease

2022-07-09

Abstract excerpt

Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disease characterized by eosinophilic hyaline intranuclear inclusions in the neurons, glial cells, and other somatic cells. Although CGG repeat expansions in NOTCH2NLC have been identified in most East Asian patients with NIID, the pathophysiology of NIID remains unclear. Intranuclear inclusions are the pathological hallmark of NIID. Previously...

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Literature Corpus work: a8c49361-452d-5af3-be44-7a7f74d84926
DOI: 10.1101/2022.07.08.499227

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